Background: Colorectal cancer is a malignancy that originates from the colon tissue, which consists of the colon and rectum. The incidence of colorectal cancer worldwide is the third largest and is the fourth leading cause of death, accounting for 11% of all cancers in human. In general, the development of colorectal cancer is an interaction between environmental factors and genetic factors. Environmental factors are divided into modifiable factors and non-modifiable factors. The recurrence rate of colorectal cancer is still very high, so it requires a precise and accurate early detection of the recurrency. Method: Comparing the accuracy of the Carcinoma Embryonic Antigen (CEA) tumor marker examination with Lactate Dehydrogenase (LDH) levels to detect colorectal cancer recurrency by using Spearman correlation analysis between two variables at Abdul Moeloek Hospital Bandar Lampung during the study period of October 2019 to September 2020. Results: Twenty one samples are obtained, 11 samples did not experience any recurrency and the other 10 samples had colorectal cancer recurrence. The mean CEA level was 139.64 U / mL and the mean LDH level was 353.10 U / L. The relationship between CEA levels and colorectal cancer recurrence was significant with a correlation coefficient of 0.663, while the relationship between LDH levels and colorectal cancer recurrence was insignificant with a correlation coefficient of 0.213. Conclusion: CEA is more accurate than LDH to predict the recurrency of colorectal cancer, so that in clinical practice CEA is better used to predict colorectal cancer recurrence.

Computed Tomography chest scan is a tool for classification of COVID 19 disease. We propose there is a relation between computed tomography severity index and inflammation biomarkers.

The article discusses the credibility of using Arsenazo III immobilized on polyacrylonitrile fiber modified with polyethylene polyamine (PPA) as a reagent for the detection of mercury ions. The optimal conditions for immobilization and complexation have been found. This is due to its high prevalence and stability in the environment, the ability to migrate and bioconcentrate, the high toxicity of most of its compounds

It was only possible because of vaccination that we were able to create a safe environment for us and animals/ pets. If it was not for rabies vaccination, we never would have kept dogs and cats as our companion animals as we do now, and we never would have been able to protect our domestic animals from diseases that not only reduce the productivity but may even be deadly. But the vaccines comes with their own adverse effects such as hypersensitivity reactions which occur due to some component of the infectious agent or one of its products; due to stabilizers like gelatin; due to adjuvants like aluminium hydroxide; due to preservatives like thiomersal; due to antibiotics like neomycin; and due to a biological culture medium like chicken embryo cells. Other adverse effects include autoimmune disorders like immune mediated hemolytic anemia, thrombocytopenia and neoplastic diseases like fibrosarcomas. Lack of efficacy, interference with diagnostic testing and other occasional suspected product-related issues have also been reported as adverse vaccination reactions. An absence of adverse reaction indicates that the immune system has not been stimulated but due to variability in the vaccines immune system, environmental conditions and the nature of the vaccine, sometimes there may be excessive stimulation of immune system thus causing serious reactions. The common reasons for occurrence of vaccine reactions are contamination of vaccines with extraneous chemical agents, failure to inactivate the vaccine organism in a killed vaccine, adverse vaccine reactions due to vaccine-induced immune suppression, adverse vaccine reactions due to excessive induction of cytokine release. Also other adverse reactions are due to human errors like administration at the wrong site or improper dilution of the vaccines, or improper storage or transportation of vaccines and thus can be minimized. Also some vaccine reactions occur due to simultaneous administration of different vaccines so is preventable. Due to a marked degree of underreporting and a bias toward more severe adverse reactions, proper data for the vaccine reactions is not available from field conditions, also due to limited number of animals used during vaccine trials, there is no accurate data even in controlled settings as to how much adverse reactions can be expected while administering a vaccine. To solve this problem post marketing surveillance for all the vaccines should be done which should involve four interrelated components, namely, data collection, analysis, interpretation, and timely dissemination. To tackle this problem of adverse vaccination reaction we can also go for double blind placebo trails as are done for drug testing in which comparison is done between vaccinated and unvaccinated group and not just one vaccinated group with other vaccinated group.

The global COVID-19 pandemic has significantly affected peoples lives, created many challenges and impacted many areas, including health, work, education, the economy and social welfare. The restrictive measures imposed to control and deal with the pandemic were many and at many different levels. Because of these measures, the majority of people were forced to stay indoors, isolated, without their daily activities, with very specific movements and with a lot of free time. On the other hand, there was a part of the population that continued to work (such as doctors, nurses, and workers in the shops of essential goods) and even in very difficult conditions. The employees in the supermarkets in particular faced a significant difficulty, since on the one hand the opening hours of the supermarkets were extended and on the other hand they were in daily contact with many different people, so they also had to manage their fear of being exposed to the virus. The present study examines the burnout and depression of workers in grocery stores during the pandemic. Specifically, the stores in which the survey was conducted were two large supermarkets of the SKLAVENITIS chain in the area of ??Elefsina and Psychiko in the Prefecture of Attica and it appeared that the employees showed moderate emotional exhaustion during the COVID-19 pandemic.

Background: Pressure ulcers are areas of localized injury to the skin, underlying tissue or both, usually over a bony prominence, as a result of pressure or in combination with shear. There are common problem in health care and represent a significant burden on patients, their relatives and caregivers.